A TRUCK driver has narrowly avoided serious injuries after running off the side of the Hume Highway.

The white Xtra Transport Services B-double had been travelling southbound on Thursday night.

The vehicle left the right side of the road about 10pm and collided with several trees before coming to a stop in the median strip.

The incident occurred several kilometres south of Holbrook and the 55-year-old driver was taken to Albury hospital.

The man had non-life threatening injuries.

The accident occurred in wet conditions and the truck became bogged down to its axles in dirt and mud.

Heavy haulage equipment was brought in for a lengthy removal process which required the southbound lanes of the road to be closed to traffic for a short period of time.

The towing job was made more difficult by the wet weather.

The driver from the Sydney-based company had narrowly avoided several large trees but the truck cabin was damaged by smaller trees and bushes.

Police attended the scene and helped with traffic control as the area was cleared.

The crash was one of several incidents emergency services have responded to in recent days as extensive rain and strong winds caused problems.