Police are appealing for witnesses following a bicycle crash that has left a man in hospital with serious injuries.

About 3.30am (Saturday 11 July 2015), a taxi driver came across a bicycle rider lying on the footpath on Glebe Road, about 150m west of Stewart Avenue.

The 30-year-old rider was found bleeding and was unable to recall how the incident occurred.

The taxi driver contacted emergency services who attended a short time later.

The man was treated at the scene by NSW Ambulance Paramedics and taken to John Hunter Hospital with multiple facial fractures.

Officers from Newcastle City Local Area Command also attended and commenced inquiries.

Initial investigations suggest the man was cycling in an easterly direction before colliding with the gutter and was ejected over the handlebars into a tree.

It is believed the rider was not wearing a helmet at the time of the collision.

Officers are investigating how the man came to be ejected from the bicycle and are appealing for anyone with information to come forward.

Anyone who may have witnessed the incident is asked to contact Newcastle Police on (02) 4929 0999 or Crime Stoppers on 1800 333 000.

Police are urging anyone with information in relation to this incident to call Crime Stoppers on 1800 333 000 or use the Crime Stoppers online reporting page: https://nsw.crimestoppers.com.au/ Information you provide will be treated in the strictest of confidence. We remind people they should not report crime information via our Facebook and Twitter pages.